Pay in installments of $27.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 29 - Sep 3
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
IFN-alpha/beta R1 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms IFNAR1,IFNAR,CRF2 1,IFN R 1,IFNAR 1 Accession P17181 1 Amino Acid Sequence Target (Lys28 Lys436) with hIgG1 Fc at C Terminus Expression System HEK293 Molecular Weight 90 120 KDa(Reducing) Purity 95% by SDS PAGE &90% by SEC HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag Human IgG1 Fc Storage Buffer PBS PH7. 4 5% trehalose Stability & Storage 12 months from date of receipt, lyophilized powder stored at
Product Specification
| Species | Human |
| Synonyms | IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1 |
| Accession | P17181-1 |
| Amino Acid Sequence | Target (Lys28-Lys436) with hIgG1 Fc at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 90-120 KDa(Reducing) |
| Purity | ＞95% by SDS-PAGE &＞90% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human IgG1 Fc |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Jacob RA, Zhang A, Ajoge HO, D'Agostino MR, Nirmalarajah K, Shigayeva A, Demian WL, Baker SJC, Derakhshani H, Rossi L, Nasir JA, Panousis EM, Draia AN, Vermeiren C, Gilchrist J, Smieja N, Bulir D, Smieja M, Surette MG, McArthur AG, McGeer AJ, Mubareka S, Banerjee A, Miller MS, Mossman K. Sensitivity to Neutralizing Antibodies and Resistance to Type I Interferons in SARS-CoV-2 R.1 Lineage Variants, Canada. Emerg Infect Dis. 2023 Jul;29(7):1386-1396. |
Background
Interferon alpha/beta receptor 1 (IFNAR1), also known as Cytokine receptor class-II member 1 (CRF2-1) or Type I interferon receptor 1, belongs to the type II cytokine receptor family. It contains four fibronectin type-III domains and pairs with IFNAR2 to form the type I interferon receptor. IFNAR1 serves as the receptor for interferons alpha and beta. Notably, IFNAR1 can transduce IFNβ signals independently of IFNAR2, without activating the Jak-STAT pathway.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy