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Description
ARPC5/p16 ARC Recombinant Rabbit mAb (S-3564-23)Product Specification Host Rabbit Antigen ARPC5 p16 Synonyms Actin related protein 2 3 complex subunit 5; Arp2 3 complex 16 kDa subunit (p16 ARC); ARC16 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Cell projection Accession O15511 Clone Number S 3564 23 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt, Mk Positive Sample THP 1, HeLa, A549, PANC 1, PC 3, NIH 3T3, PC 12, COS 7 Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | ARPC5/p16 |
| Synonyms | Actin-related protein 2/3 complex subunit 5; Arp2/3 complex 16 kDa subunit (p16-ARC); ARC16 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Cell projection |
| Accession | O15511 |
| Clone Number | S-3564-23 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | THP-1, HeLa, A549, PANC-1, PC-3, NIH/3T3, PC-12, COS-7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt, Mk |
Background
p16 ARC serves as a substrate for MAPK-activated protein kinase 2 (MAPKAPK2), which phosphorylates the protein at serine-77, potentially modulating Arp2/3 complex regulatory functions and actin cytoskeleton remodeling. As an essential component for maintaining Arp2/3 complex integrity, p16 ARC is critical for effective actin nucleation and cellular processes involving cytoskeletal dynamics.
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