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Description
Her2 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms Her2, ERBB2, CD340, HER 2 neu, MLN19, NEU, NGL, TKR1 Accession XP_005584091. 2 Amino Acid Sequence Thr23 Thr652, with C terminal His Expression System HEK293 Molecular Weight 85 95kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Cynomolgus |
| Synonyms | Her2, ERBB2, CD340, HER-2/neu, MLN19, NEU, NGL, TKR1 |
| Accession | XP_005584091.2 |
| Amino Acid Sequence | Thr23-Thr652, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 85-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Krawczyk N. et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-4024. |
Background
Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2, NEU, NGL, TKR1 and c-erb B2, and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
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4.3 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 4
Such a cutie, but my wrist was too tiny
Color: Light Blue
as most reviews stated, you need to go to a place to remove some of the pieces and make it adjustable to your wrist
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 10, 2025
★★★★★ 5
💙
Color: Light Blue
I live by the ocean 🌊 I love the ocean I love good ole Timex I love a light breezy watch on my wrist I love the blue. Why is everyone taking out the links? Wear it like a bracelet as the beautiful bracelet watch it is 💙
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 23, 2024
★★★★★ 1
Unscrupulous
Color: Light Blue
Avoid this seller. After purchasing this watch for my wife, it lost 19 minutes the first week. I contacted them and had to return it at my expense for repairs. After having it for a month, they returned it, and it again list 10 minutes in the first few days. When I contacted them today, they said it was after the return window. They have a 1.5 rating on Trust pilot, and most of their goods don't carry the original manufacturer warranty. Avoid!!!
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Nice every day watch
Color: Light Blue
Nice watch. Light weight. Great for every day. The band is large. Hangs like a bracelet. Not a problem for me. Love the color!!
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Reviewed in the United States on September 28, 2022
★★★★★ 5
Beautiful watch
Color: Light Blue
This is an absolutely beautiful watch. The workmanship is fantastic. I get many many compliments on this watch it’s a Timex!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 8, 2023
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