SKU: 9501315996

Human Thyroid peroxidase Protein, His Tag

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Description

Human Thyroid peroxidase Protein, His TagProduct Specification Species Human Synonyms TPO Accession P07202 Amino Acid Sequence Protein sequence (P07202, Phe19 Arg846, with C His Tag)

Product Specification


Species Human
Synonyms TPO
Accession P07202
Amino Acid Sequence

Protein sequence (P07202, Phe19-Arg846, with C-His Tag) FFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR

Expression System HEK293
Molecular Weight Predicted MW: 93.7 kDa Observed MW: 110 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. Thyroid peroxidase oxidizes iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), the thyroid hormones. In diagnostic immunohistochemistry, the expression of thyroid peroxidase (TPO) is lost in papillary thyroid carcinoma. Thyroid peroxidase is also a frequent epitope of autoantibodies in autoimmune thyroid disease, with such antibodies being called anti-thyroid peroxidase antibodies (anti-TPO antibodies). This is most commonly associated with Hashimoto's thyroiditis. Thus, an antibody titer can be used to assess disease activity in patients that have developed such antibodies.

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SKU: 9501315996

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Reviewed in the United States on January 27, 2026
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amessb
Bozeman, US
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Size: XX-Large, Color: Green
Very nice fabric, sizing is goood and only shrinks slightly after washing/drying. Good color selection
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Reviewed in the United States on February 24, 2026
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Chelsea, US
★★★★★ 5
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Size: X-Large, Color: Light Red
Intended to use it as an everyday shirt but the quality we much better than expected for the price so it's now a more special occasion pullover. Nice soft and comfortable material, well constructed and sewn, good loose but not baggy fit, nice heft and substance around the collar. Lightweight but not thin fabric. Excellent value = 5+ stars
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Kindle Customer
Grantham, US
★★★★★ 3
Beware of Size
Size: XX-Large, Color: White
Inconsistency in size per other reviews. The site said XL was my suggested size.....I usually follow that advice. I went XXL this time and happy I did. The neck is a medium and the rest is maybe XL....it feels "fitted" too...not very loose. I will keep it as I like a snug neck---but this needs effort to pull over my head. Having said that, the material is soft and not too thick. Just beware of sizes.
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Reviewed in the United States on October 16, 2025
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Excellence
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Excellent product, definitely will be buying more
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Reviewed in the United States on May 21, 2026

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