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Description
Her2 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms Her2, ERBB2, CD340, HER 2 neu, MLN19, NEU, NGL, TKR1 Accession XP_005584091. 2 Amino Acid Sequence Thr23 Thr652, with C terminal His Expression System HEK293 Molecular Weight 85 95kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Cynomolgus |
| Synonyms | Her2, ERBB2, CD340, HER-2/neu, MLN19, NEU, NGL, TKR1 |
| Accession | XP_005584091.2 |
| Amino Acid Sequence | Thr23-Thr652, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 85-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Krawczyk N. et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-4024. |
Background
Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2, NEU, NGL, TKR1 and c-erb B2, and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
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Exchange/Return Notes
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4.3 ★★★★★
Based on 25 reviews
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Product Reviews
★★★★★ 5
Best Gift
Color: 2856 All Black Face/Black Band
“This watch was the perfect gift for my dad. It looks classy, feels high-quality, and suits him perfectly. Every time he wears it, it reminds him of how much he is loved and appreciated. Seeing the smile on his face made it even more special. A meaningful and timeless gift for any father.”
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Reviewed in the United States on May 26, 2026
★★★★★ 5
Perfect gift
Color: 2856 Silver Black Face/Silver Band
Got it for a birthday gift and he loves it. The style was perfect. Great choice.
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Reviewed in the United States on May 12, 2026
★★★★★ 5
Feels cheap, but so far it's held up
Color: 2926 Silver Green
Looks as advertised, works well, and pretty water resistant thus far. Surprisingly water resistant. Unfortunately the band the watch comes with immediately felt a little cheap and flimsy to me. About a week after my purchase the band did inevitably break. The watch itself is still fantastic and everything works proper, like it should. Funny thing, I had left a review shortly after my purchase, talking about my dissatisfaction with how cheap the band felt. I have purchased many Olevs watches in the past and have had zero issues with any of them. I guess the company that makes or sells these watches read my review and asked about my dissatisfaction. I informed them of what happened, and they offered me a full refund. Originally I posted my review at three stars, just for that watch. All the other Olevs watches I have purchased are great. The customer service is so fantastic, this has never happened to me before so I am elated. They earned the five-star rating, and I would highly recommend checking out their collection of watches if you are a collector like me. I am overly confident if you do purchase one of these watches, and have any issue whatsoever with it, if you contact the customer service department they will be incredibly helpful as they have with me, and based off of my recent experience, I am sure they will do whatever it takes to make things right with you. Well done, very surprising customer service department. Very refreshing these days. Based on customer satisfaction alone they get five stars from me!
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Reviewed in the United States on August 26, 2025
★★★★★ 4
Nice watch, cheap band sizing tool.
Color: 2856 All Black Face/Black Band
Nice watch, but watch band link removal tool is made of plastic and broke when trying to size the watch band.
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Reviewed in the United States on May 19, 2026
★★★★★ 5
Looks Awesome
Color: 2856 Silver Black Face/Silver Band
Bought this for our son for a fun watch and he loves it !
Looks amazing ! It did take a little bit of time to make it fit his wrist , but after that it was great
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Reviewed in the United States on May 4, 2026
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