SKU: 14997271554

Alexa Fluor® 488 Mouse Anti-Human CD56 Antibody (S-577-58)

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Description

Alexa Fluor® 488 Mouse Anti-Human CD56 Antibody (S-577-58)Product Specification Host Mouse Antigen CD56 Synonyms Neural cell adhesion molecule 1; N CAM 1; NCAM 1; NCAM; NCAM1 Immunogen Recombinant Protein Location Cell membrane Accession P13591 Clone Number S 577 58 Antibody Type Mouse mAb Isotype IgG1, Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 30

Product Specification


Host Mouse
Antigen CD56
Synonyms Neural cell adhesion molecule 1; N-CAM-1; NCAM-1; NCAM; NCAM1
Immunogen Recombinant Protein
Location Cell membrane
Accession P13591
Clone Number S-577-58
Antibody Type Mouse mAb
Isotype IgG1,λ
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 30

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Hu

Background

Neural cell adhesion molecule 1 (NCAM-1), also known as CD56, is a cell adhesion protein belonging to the immunoglobulin superfamily. It is expressed on various cell types including neurons, muscle cells, and immune cells like natural killer (NK) cells. NCAM-1/CD56 plays crucial roles in cell-to-cell and cell-matrix interactions during development and differentiation, regulating processes such as neurogenesis, neurite outgrowth, axonal guidance, and cell migration in the nervous system. In the immune system, it is involved in the expansion of T lymphocytes, B lymphocytes, and NK cells. NCAM-1/CD56 also triggers signaling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). Additionally, it serves as a biomarker for certain diseases, such as malignant tumors in the nervous system and neuroendocrine carcinoma.

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SKU: 14997271554

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4.5 ★★★★★
Based on 15 reviews
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Product Reviews
A
Verified Purchase
Anne L
Lexington, US
★★★★★ 5
Long lasting dog treat
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
My dog absolutely loved this stuffed shin bone—it kept her occupied way longer than most treats, which is always a win. It’s a great option when you need something that will actually hold their attention. What I Loved:    •   Long-lasting chew compared to typical treats    •   The stuffing inside keeps dogs interested and engaged    •   Helps with boredom and keeps them busy    •   Once finished, the bone can be reused with other fillings One Small Con:    •   It can get a little messy depending on how your dog chews, so it’s best to give it in an easy-to-clean area Who It’s Best For: Perfect for medium to strong chewers or dogs that need something to keep them occupied for a while. Final Verdict: This is a great value and a go-to for keeping dogs entertained. I’d definitely recommend it if you’re looking for a longer-lasting treat that your dog will actually stick with! 🐾
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Reviewed in the United States on April 11, 2026
N
Verified Purchase
nappydrew
Charlottesville, US
★★★★★ 5
🦴 The Ultimate Distraction: A Must-Have for Power Chewers!
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
Finding a chew toy that can withstand my 70-pound "House Hippo" (an expert-level destructor) for more than ten minutes felt impossible, until we discovered these stuffed shin bones. These treats are an absolute game-changer for long-lasting entertainment, durability, and distraction. Exceptional Durability and Value: The bone itself is thick, natural, and surprisingly sturdy. Unlike processed chews that crumble or get demolished instantly, these last for days of chewing. The value is tremendous because they provide two phases of entertainment: first, the intense effort of licking out the filling, and second, the satisfying work of chewing the bone itself afterward. Irresistible Appeal (Peanut Butter/Cheese Filling): The filling is the secret weapon! My dog goes absolutely wild for the flavor. The filling is firmly packed inside, which means he has to spend a significant amount of time actively working to get every last bit. This intense focus buys me hours of peace and quiet, which is invaluable. On top of that, they offer good nutrition! Less Mess, More Fun: I appreciate that these bones are relatively neat. They don't leave greasy residue all over the carpet like some marrow bones, and the durable exterior means minimal splintering (though, as with any bone, supervision is required). They satisfy my dog's natural chewing instinct while promoting dental health by scraping against his teeth as he works the chew. Final Verdict: If you have an aggressive chewer who needs a serious, long-lasting treat that is both entertaining and structurally sound, look no further. These stuffed bones deliver on their promise and are now a staple in our dog treat rotation!
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Reviewed in the United States on October 4, 2025
M
Verified Purchase
Mandi Mills
New York, US
★★★★★ 5
Still Going Strong Months Later
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
These stuffed chew bones have been amazing for my dogs. Even months later, they’re still happily chewing on them, and that says a lot since they’re aggressive chewers. The bacon and cheese filling keeps them interested, and the bones themselves are durable enough to handle their chewing without falling apart. After all this time, the chews are still holding up and my dogs love them every time. They keep my dogs busy, help with dental care, and are definitely worth having on hand for large dogs who love to chew. Durable, tasty, and long-lasting—can’t ask for more.
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Reviewed in the United States on February 10, 2026
C
Verified Purchase
Christy
Houston, US
★★★★★ 5
Long lasting
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
These are the longest lasting bones I have ever purchased. But if you don't want a heavy bone that makes noise when dropped this is not for you. They go sliding across my floor as they are being tossed around and played with. But they love them and they have lasted for months. I am glad they are not as expensive as others. To many things are over priced. Dogs love them.
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Reviewed in the United States on May 14, 2026
A
Verified Purchase
Amazon Customer
Port Orchard, US
★★★★★ 4
Arrived on time and as described
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
It is perfect for my 120 lb dog. He did give up after 6 hours of trying to get the “stuffing” out. The bone held up to his chewing. He loved it!
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Reviewed in the United States on January 14, 2026

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