SKU: 22535476261

LIF Protein, Human (GMP)

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Description

LIF Protein, Human (GMP)Product Specification Species Human Synonyms Leukemia inhibitory factor; LIF; Differentiation stimulating factor (D factor); Melanoma derived LPL inhibitor (MLPLI); Emfilermin; Accession P15018 Amino Acid Sequence Ser23 Phe202 Expression System E. coli Mycoplasma Sterility phValue 7. 8~8. 2 ProteinContent 90%~120% SdsPageMolecularWeight 202kD SdsPagePurity 97% RpHplcPurity 95% SecHplcPurity 97% CellActivity < 0. 3ng ml Conjugation Unconjugated Tag No

Product Specification


Species Human
Synonyms Leukemia inhibitory factor; LIF; Differentiation-stimulating factor (D factor); Melanoma-derived LPL inhibitor (MLPLI); Emfilermin;
Accession P15018
Amino Acid Sequence

Ser23-Phe202

Expression System E.coli
Mycoplasma 阴性
Sterility 符合
phValue 7.8~8.2
ProteinContent 90%~120%
SdsPageMolecularWeight 20±2kD(还原)
SdsPagePurity ≥97%(非还原)
RpHplcPurity ≥95%
SecHplcPurity ≥97%
CellActivity < 0.3ng/ml
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

20mM Tris, 200mM NaCl, pH8.0

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.

Reference

Development. 2005 Mar;132(5):885-96.
Nat Med. 2019 May;25(5):838-849.
Cell. 2015 May 7;161(4):933-45.

Background

Leukemia Inhibitory Factor (LIF) is a member of the IL-6 family of cytokines. It is a multifunctional glycoprotein with a molecular weight ranging from 28 to 45 kDa, depending on the expression system and post-translational modifications. LIF is composed of a signal peptide, an extracellular domain, and an intracellular domain, which collectively endow it with diverse biological functions. LIF is expressed in various tissues, including the liver, lungs, heart, nervous system, and immune cells, highlighting its widespread distribution and significance.
LIF is a critical cytokine widely used in biomedical research, particularly in stem cell biology and regenerative medicine. It also plays a crucial role in maintaining the pluripotency and inducing the differentiation of stem cells, the treatment of neurodegenerative diseases, the modulation of inflammatory responses.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 22535476261

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Reviewed in the United States on December 21, 2023
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Jorge Amagua
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★★★★★ 5
Diseño increíble por el precio
El reloj es demasiado bonito u de una buena calidad tomando en cuenta el precio, lo único que no me gusto es el cristal que como se describe es tipo diamante desde ciertos ángulos impide ver la carátula del reloj pienso en llevarlo a un relojero a cambiar por un cristal plano, me gustaría comprarlo en otros colores tiene muchas variedades y todos lucen bonitos
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