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Description
TfR/CD71 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90 Accession A0A2K5X958 Amino Acid Sequence Cys89 Phe760, with N terminal 10*His
Product Specification
| Species | Cynomolgus |
| Synonyms | CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90 |
| Accession | A0A2K5X958 |
| Amino Acid Sequence | Cys89-Phe760, with N-terminal 10*His HHHHHHHHHHGGGSGGGSCKGVEPKTECERLAGTESPAREEPEEDFPAAPRLYWDDLKRKLSEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQVKDSAQNSVIIVDKNGGLVYLVENPGGYVAYSKAATVTGKLVHANFGTKKDFEDLDSPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKFPIVKADLSFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCKMVTSENKSVKLTVSNVLKETKILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTMQDVKHPVTGRSLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCEDTDYPYLGTTMDTYKELVERIPELNKVARAAAEVAGQFVIKLTHDTELNLDYERYNSQLLLFLRDLNQYRADVKEMGLSLQWLYSARGDFFRATSRLTTDFRNAEKRDKFVMKKLNDRVMRVEYYFLSPYVSPKESPFRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQGAANALSGDVWDIDNEF |
| Expression System | HEK293 |
| Molecular Weight | 83-90kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Kawabata H. (2019) Transferrin and transferrin receptors update. Free Radic Biol Med. 133:46-54. 2、Daniels T R. et al. (2006) The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. Clin Immunol. 121: 144-158. |
Background
The major protein essential for the uptake of iron is transferrin receptor (TfR), encoded by TFRC, which is found primarily as a homodimer. TfR is a type II transmembrane glycoprotein that is endocytosed from the cell membrane after binding iron with transferrin (Tf), a serum iron carrier protein. TfR was found to affect many aspects of tumorigenesis, such as cancer cell proliferation, migration, invasion, metastasis and apoptosis. TfR expression was consistent with the asthma severity index, especially the proinflammatory M1 macrophage phenotype. TfR expression may be a good marker to indicate asthma severity. Increased TfR expression and decreased methylation levels of TfR were strongly correlated with multiple clinicopathological parameters. Elevated TfR expression was associated with a poor survival rate in BC patients. TfR is a new independent prognostic biomarker and a potential target for immunotherapy in BC.
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4.9 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
It operates just like a brand new Apple iPad
Color: Silver, Memory Storage Capacity: 32 GB, Size: Wi-Fi
The item works great. It hasn’t given me any issues. The battery lasts pretty long clean no scratches no bumps only thing the charger didn’t work, but that’s not a big deal. The tablet is extremely loud. The quality is great. The screen quality is also great strong. It’s just like a brand new tablet the touch screen it’s normal. It works just like a brand new tablet. Everything is great on this tablet. Haven’t had no issues and I’ve always bought used tablets and it was worth the Buy worth the money.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 8, 2026
★★★★★ 5
Works great
Color: Space Gray, Memory Storage Capacity: 32 GB, Size: Wi-Fi
Nice. Great condition. Battery lasts. Came packaged well. Glad I purchased.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 30, 2026
★★★★★ 4
Reliable everyday iPad with smooth performance but limited storage sadly
Color: Silver, Memory Storage Capacity: 32 GB, Size: Wi-Fi, Color: Silver, Memory Storage Capacity: 32 GB, Size: Wi-Fi
The Apple 7th Generation iPad has been a very reliable device for everyday use. It runs smoothly when browsing, streaming videos, using social media, and handling basic apps without lag. The 10.2-inch screen is a great size big enough for comfort but still easy to carry around. The display is clear and bright, and the battery life holds up well for daily use. Setup was quick and simple, and it connects easily to Wi-Fi and Bluetooth accessories. The main downside is the 32GB storage. It fills up very fast, especially with apps, updates, and photos, so it works best if you rely on cloud storage or don’t download a lot.
Overall, this is a solid and dependable iPad for students, casual users, or anyone who needs a simple IPAD for everyday tasks, Also I’ve had this iPad for about 3 months now… still in great condition
Update : I’ll have to remove a star since the iPad dies very fast out of nowhere unfortunately :(
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Snug fit…as it should be!
Color: Crystal Clear
Fits well and the screen protector and keyboard cover is a nice touch. The bag included will work well with my new Bluetooth mouse! Well worth the price and it doesn't hide the color - crystal clear!
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Reviewed in the United States on April 27, 2026
★★★★★ 5
Perfect Laptop Case
Color: Crystal Clear, Color: Crystal Clear
I am always worried about cases like these because I dont want them to make the laptop bulky. But this case is actually really great. Fits perfect with the neo and was easy to put it together. Holds up well, very durable and looks great. Quality of the case is perfect. Highly recommend if in search of a cool sleek case for your laptop.
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Reviewed in the United States on May 21, 2026
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