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Description
Human Desmoglein 3, His tagProduct Specification Species Human Synonyms 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 Accession P32926 Amino Acid Sequence Protein sequence(Q29432, Arg54 Val380, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 |
| Accession | P32926 |
| Amino Acid Sequence | Protein sequence(Q29432, Arg54-Val380, with C-10*His) RGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFCTSPACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPFGLSIEEYGFEGRIYDGVLGLNYPNISFSGAIPIFDKLKNQRAISEPVFAFYLSKDEREGSVVMFGGVDHRYYEGELNWVPLIQAGDWSVHMDRISIERKIIACSDGCKALVDTGTSDIVGPRRLVNNIHRLIGAIPRGSEHYVPCSEVNTLPSIVFTINGINYPVPGRAYILKDDRGRCYTTFQENRVSSSTETWYLGDVFLRLYFSVFDRGNDRIGLARAVGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:17.6kDa Actual:20-30kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1. Desmoglein-3, along with Desmoglein-1, has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. The mucosal dominant form of pemphigus vulgaris only involves antibodies against Desmoglein-3 and causes mucosal erosions, but no skin lesions. Desmoglein-3 serves as a prognostic marker of Esophageal Squamous Cell Carcinoma (ESCC), and may even be involved in the progression of ESCC.
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Exchange/Return Notes
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4.8 ★★★★★
Based on 12 reviews
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Product Reviews
★★★★★ 5
Nice bag
Size: One Size, Color: Rose Quartz
Great bag, good size. I bought another guitar strap that also matches perfectly.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 30, 2026
★★★★★ 5
Great quality, even better price
Size: One Size, Color: Lemongrass
Very awesome purse!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 31, 2026
★★★★★ 4
A little disappointed
Size: One Size, Color: Tuscany
A little disappointed. Bag is a good size but the color is not the same as another Lucky Brand bag that I was trying to replace. It’s darker and not a true tan leather. The crossbody clip on is not leather.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 9, 2026
★★★★★ 5
Lucky Brand at Amazon Prices
Size: One Size, Color: Rose Quartz
Who doesnt love the smell of a new leather purse? And from Lucky Brand at Amazon prices? Sign me up! I plan to use this as a crossbody as the strap is the perfect length. So cute, great size and smells fantastic.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 23, 2025
★★★★★ 3
Love the style but it doesn’t hold shape
Size: One Size, Color: Vanilla
I am big fan of the Lucky Brand. This tote disappointed simply because it was floppy. So if you set it down it just collapses instead of holding shape. So it wasn’t what I was looking for in a tote. I was really excited about this bag because I love the style and color. But I ended up returning it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 19, 2026
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