SKU: 59863304929

Mouse Anti-Human TCR α/β Antibody (S-R686)

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Description

Mouse Anti-Human TCR α/β Antibody (S-R686)Product Specification Host Mouse Antigen TCR Synonyms TCR; TCR Location Cell membrane Accession P01848 P01850 Clone Number S R686 Antibody Type Mouse mAb Application FCM Reactivity Hu Positive Sample Human PBMC Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Dilution application dilution species FCM 1: 200 Hu

Product Specification


Host Mouse
Antigen TCR α/β
Synonyms α/β TCR; TCR α/β
Location Cell membrane
Accession P01848、 P01850
Clone Number S-R686
Antibody Type Mouse mAb
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:200 Hu

Background

The T cell receptor (TCR) α and β proteins are essential components of the αβ T cell receptor, a heterodimeric surface protein expressed on T lymphocytes that recognizes antigenic peptides presented by major histocompatibility complex (MHC) molecules. The TCR α chain is encoded by the TRAC (T cell receptor alpha constant) and TRAV (T cell receptor alpha variable) genes, while the TCR β chain is encoded by the TRBC (T cell receptor beta constant) and TRBV (T cell receptor beta variable) genes, along with diversity (TRBD) and joining (TRBJ) segments, enabling extensive combinatorial diversity. Structurally, both chains consist of a variable (V) domain responsible for antigen recognition and a constant (C) domain that anchors the receptor to the cell membrane. The TCR αβ heterodimer associates with the CD3 complex (CD3γε, CD3δε, and CD247 ζζ) to form a functional TCR-CD3 signaling unit, which transmits activation signals upon peptide-MHC engagement. TCR β undergoes V(D)J recombination during thymic development, contributing to the receptor's antigen specificity, whereas TCR α lacks a D segment but still undergoes recombination for diversity. Mutations or dysregulation in TCR α/β genes can lead to immune disorders, including T cell malignancies and autoimmune diseases. TCR αβ T cells are critical for adaptive immunity, mediating responses against infections, tumors, and self-antigens in autoimmune conditions.

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SKU: 59863304929

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Ms Cox
Alexandria, US
★★★★★ 5
Strong and durable
My everyday plates..cheap enough and strong enough ..buy all the time for microwaving and leftovers..they are strong enough to keep for a second round at the table
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Reviewed in the United States on May 15, 2026
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mary2013
Carnegie, US
★★★★★ 5
Good price
Size: 200 Count (Pack of 1)
Great quality
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Reviewed in the United States on May 26, 2026
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Robin
Natrona Heights, US
★★★★★ 5
Best paper plates I've bought in years. I hope Amazon sticks with this supplier!.
Size: 200 Count (Pack of 1)
These paper plates were marked South Korea. They are strong, that don't stick together, the price is right. Love them, just hope the same kind are delivered with this order! We'll find out soon.
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Reviewed in the United States on March 29, 2026
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Elisabeth F.
Omaha, US
★★★★★ 5
Uncoated
Size: 200 Count (Pack of 1)
One of the few offering low cost plates without coatings, often plastic
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Reviewed in the United States on March 20, 2026
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didimention
Grantham, US
★★★★★ 4
Very lightweight but good everyday
Size: 500 Count (Pack of 1)
These are great for everyday use. I use them under bowls when I microwave, to collect pieces of food that I’m going to throw away while I’m cooking. Good enough for toast or a microwaved muffin. They are lightweight and not meant for heavy amounts of food.
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Reviewed in the United States on May 14, 2026

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