SKU: 64096596315

Human Fascin, His tag

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Description

Human Fascin, His tagProduct Specification Species Human Synonyms 55 kDa actin bundling protein, Singed like protein, p55, FAN1, HSN, SNL Accession Q16658 Amino Acid Sequence Protein sequence(Q16658, Met1 Tyr493, with C 10*His)

Product Specification


Species Human
Synonyms 55 kDa actin-bundling protein, Singed-like protein, p55, FAN1, HSN, SNL
Accession Q16658
Amino Acid Sequence

Protein sequence(Q16658, Met1-Tyr493, with C-10*His)
MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFNDGAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKASAETVDPASLWEYGGGGSHHHHHHHHHH
Expression System E.coli
Molecular Weight Theoretical: 56.2kDa Actual: 56kDa
Purity

>95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 0.1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, -20 to -70 °C as supplied. 
· 6 months, -20 to -70 °C under sterile conditions after reconstitution.
· 1 week, 2 to 8 °C under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.

Background

Fascin is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin (from the Latin for bundle) is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins. It is calcium insensitive and monomeric. Abnormal fascin expression or function has been implicated in breast cancer, colon cancer, esophageal squamous cell carcinoma, gallbladder cancer, pancreatic cancer, and prostate cancer. It is also helpful in identifying Hodgkin cells.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 64096596315

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4.8 ★★★★★
Based on 18 reviews
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Product Reviews
D
Verified Purchase
Danielle L Dykhouse
Houston, US
★★★★★ 5
Dog approved.
Size: X-Large, Color: Cheese
I’m a 70 lbs Goldendoodle (supposed to be 65, don’t ask) and I love cheese. Real cheese. Sharp cheddar with sourdough bread is my dream, but apparently I’m “on a health journey,” so my people bought me this instead. Does this bone actually taste like cheese? No. I am not fooled. Do I still enjoy chewing it loudly while my humans are trying to watch TV? Absolutely yes. This bone satisfies my need to chew and my emotional desire for cheese-adjacent activities. It keeps me busy, saves the furniture, and lets me crunch dramatically during important dialogue scenes. The yellow color is nice — very cheese-coded — although some cheeses are white, so just something to consider for future versions. Also, good news: it doesn’t smell like cheese at all, which my humans seem very grateful for. Apparently they don’t want the carpet to smell like a deli. Weird. Final verdict: Not cheese. Still enjoyable. Would chew again. ~Barley
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 4, 2026
D
Verified Purchase
Dez F.
Carnegie, US
★★★★★ 5
A Humorous Twist on Tough Dog Toys!
Size: Large, Color: Lobster 3 Pack
I recently purchased the Nylabone Power Chew Dog Toy Pack for Aggressive Chewers from Amazon, and I must say, these toys have been a hilarious hit with my furry friend. As a dog parent of a strong and determined chewer, finding toys that can withstand their chewing prowess is a top priority, and these toys deliver both durability and a touch of humor. The pack consists of three large/giant-sized toys in the shape of a lobster, cheese, and broccoli. The unique and amusing design puts a smile on my face every time I see my dog interacting with them. The unexpected twist brings a playful element to our daily playtime sessions, making it a fun and engaging experience for both of us. When it comes to durability, these toys excel. My dog can be quite aggressive with their chewing, and I've struggled to find toys that can withstand their powerful jaws. However, the Nylabone Power Chew toys have proven to be impressively tough and durable. Despite rigorous chew sessions, these toys have remained intact, with no signs of wear or damage. They provide a reliable outlet for my dog's chewing instincts without the risk of shredding or ingesting any harmful materials. The textured surfaces of these toys add an extra layer of interest for my dog. The ridges and raised bumps provide sensory stimulation, promoting healthy oral hygiene and helping to clean teeth and gums as they chew. I appreciate the added dental benefits these toys offer, as it helps maintain my dog's dental health while they engage in play. I also appreciate the size options available in this pack. Large and giant-sized dogs often require bigger toys to accommodate their larger mouths and chewing strength. The included toys are appropriately sized for larger breeds, ensuring a comfortable grip and maximum enjoyment during play sessions. As a bonus, these toys are made from high-quality, non-toxic materials, so I have peace of mind knowing that my dog can safely interact with them. Safety is a top priority for me, and Nylabone consistently delivers in that regard. In conclusion, if you have an aggressive chewer and are in search of durable, funny, and engaging dog toys, the Nylabone Power Chew Dog Toy Pack is a fantastic choice. These toys provide hours of entertaining play, withstand even the most determined chewers, and offer dental benefits. Embrace the humorous twist and enjoy watching your furry friend engage in safe and engaging play with these fantastic toys. Invest in the Nylabone Power Chew Dog Toy Pack today and let the lobsters, cheese, and broccoli bring laughter and durability to your dog's playtime!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 19, 2023
K
Verified Purchase
Kirstyn Shearer
Charlottesville, US
★★★★★ 5
Solid win for any chewing pup!
Size: Small, Color: Broccoli 3 Pack, Size: Small, Color: Broccoli 3 Pack
My pup loves them! Long lasting plus health benefits for his teeth, 10/10 would recommend 💖
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 27, 2026
S
Verified Purchase
Stef
Louisville, US
★★★★★ 5
Shark dog approved
Size: Large, Color: Broccoli, Size: Large, Color: Broccoli
My new baby shark.... I mean puppy really enjoys chewing. I can't just give her a ton of pig ears or bully sticks all day, which she would definitely love, so I'm constantly looking for well made chew toys. I'd put this right up with Kong. Very durable and nice. I also love the different textures, she seems to also love it. She can gnaw at the top and chew on the stem. She wanted it as soon as I opened it - it does smell like bacon but I haven't taken a chomp at it to be able to write a complete review! My dog is about 23 lbs but I can see a 80 lb dog chew this, it's not small.
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Reviewed in the United States on October 8, 2025
N
Verified Purchase
Nunya B
Louisville, US
★★★★★ 4
So cute
Size: Large, Color: Pumpkin
My French Bulldogs have really strong jaws and are aggressive chewers. These really are sturdy and last a good amount of time. They are a bit heavy and awkward for my dogs to hold onto but they do like them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2026

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