SKU: 79863547982

Human LCK, His tag

Sale price$76.50 Regular price$85.00
Save 10%

Pay in installments of $21.25 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 25 - Aug 30

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Human LCK, His tagProduct Specification Species Human Accession P06239 Amino Acid Sequence Protein sequence(P06239, Asn64 Thr226, with C 10*His) NLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight Theoretical: 20. 1kDa Actual: 24 30kDa Purity >90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated

Product Specification


Species Human
Accession P06239
Amino Acid Sequence

Protein sequence(P06239, Asn64-Thr226, with C-10*His)
NLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Theoretical: 20.1kDa Actual: 24-30kDa
Purity

>90% by SDS-PAGE

Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage
  • 12 months from date of receipt, -20 ℃ to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.  
  • Please avoid repeated freeze-thaw cycles. 

Background

Lymphocyte-specific protein tyrosine kinase (LCK) is a member of the Src family of protein tyrosine kinases (PTKs). It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK has emerged as one of the key molecules regulating T-cell functions. Studies using LCK knock-out mice or LCK-deficient T-cell lines have shown that LCK regulates the initiation of TCR signaling, T-cell development, and T-cell homeostasis. Because of the crucial role of LCK in T-cell responses, strategies have been employed to redirect LCK activity to improve the efficacy of chimeric antigen receptors (CARs) and to potentiate T-cell responses in cancer immunotherapy. In addition to the well-studied role of LCK in T cells, evidence has been accumulated suggesting that LCK is also expressed in the brain and in tumor cells, where it actively takes part in signaling processes regulating cellular functions like proliferation, survival and memory. Therefore, LCK has emerged as a novel druggable target molecule for the treatment of cancer and neuronal diseases. 

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 79863547982

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.8 ★★★★★
Based on 9 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
R
Verified Purchase
Reviewed@Home
Draper, US
★★★★★ 5
Good Value
Color: Black, Size: 9.25″, Color: Black, Size: 9.25″
This sink caddy is really practical and helps keep the kitchen sink area organized. It holds sponges and brushes neatly, and the self-draining design works well to keep things from getting soggy. A simple but very useful addition to the kitchen.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
S
Verified Purchase
SMorgan
Louisville, US
★★★★★ 5
Because the base is slanted the water drains well and doesn't sit.
Color: Black, Size: 9.25″
Works great. Love the product!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 3, 2026
L
Verified Purchase
Lynn Kato
West Palm Beach, US
★★★★★ 5
Looks good in the bathroom.
Color: Gold, Material Type: Stainless Steel, Color: Gold, Material Type: Stainless Steel
The quality of this product was excellent. Very sturdy. Easy to assemble. Just what I was looking for. When getting the paper towels, the base did not move all around. Highly recommend for the price.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 18, 2026
C
Verified Purchase
Chantell Leatta
Boise, US
★★★★★ 5
very nice
Color: Black, Material Type: Stainless Steel
Easy to assemble. Easy to Clean. Very standard nothing insane, good price point for the quality and durability.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
H
Verified Purchase
Hannah Glidewell
Phoenix, US
★★★★★ 5
Lightweight but I like it
Color: Black, Material Type: Stainless Steel
Honestly fantastic for the price. It's just heavy enough to not get yanked around. It's pretty. And it has not looked like it has any wear or anything yet. I would recommend it. Especially for the price. If you want something a little bit more heavy duty I would definitely go with something else but I've had no issues
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 26, 2025

recommand products