SKU: 86981487592

Pacific Blue Armenian hamster Anti-Mouse CD3 Antibody (S-R491)

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Description

Pacific Blue Armenian hamster Anti-Mouse CD3 Antibody (S-R491)Product Specification Host Armenian hamster Antigen CD3 Synonyms T cell surface glycoprotein CD3 zeta chain; T cell receptor T3 zeta chain; Cd3z; Tcrz; Cd247 Location Cell membrane Accession P24161 Clone Number S R491 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1%

Product Specification


Host Armenian hamster
Antigen CD3
Synonyms T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; Cd3z; Tcrz; Cd247
Location Cell membrane
Accession P24161
Clone Number S-R491
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD3, also known as the cluster of differentiation 3, is a protein complex found on the surface of T cells, playing a crucial role in the immune system. It consists of four distinct chains: CD3γ, CD3δ, CD3ε, and CD3ζ. These chains form a complex that associates noncovalently with the T-cell receptor (TCR) to form the TCR complex, which is essential for recognizing antigens presented by major histocompatibility complex (MHC) molecules. When the TCR binds to an antigen-MHC complex, the CD3 complex transmits signals into the T cell, initiating a cascade of intracellular events that lead to T cell activation, proliferation, and differentiation. This process is vital for the immune response against pathogens and abnormal cells. CD3 is also involved in T cell development and maturation in the thymus. Given its central role in T cell function, CD3 is a key target in immunotherapy for diseases such as cancer and autoimmune disorders.

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Exchange/Return Notes
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SKU: 86981487592

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Alexandria, US
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For the money you spend, you can't beat it.
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Citizen has the best watches for the money you spend. Can't beat the prices.
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Very nice watch love it and the price
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Osman
Massapequa, US
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the nicest watch I've used recently
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Reviewed in the United States on April 5, 2026
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D. Jeffrey Eells
New York, US
★★★★★ 4
As described..handsome watch
Style: Dress, Color: Two-Tone Gold/ Blue Dial
Christmas gifts my sons will remember..beautiful watch. Easy to adjust the bracelet if you buy the kit..
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Reviewed in the United States on February 9, 2025
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Christopher A. Smith
Houston, US
★★★★★ 5
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Style: Dress, Color: Two-Tone Gold/ Blue Dial
Absolute great watch. It’s perfect for an every day and situation from work to date night. I had to take out 4 links and now it fits perfectly!
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Reviewed in the United States on July 5, 2025

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